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Expert help for dry skin

Expert help for dry skin

The Eucerin line-up
The Eucerin range offers a wide choice of products that can be used separately for specific areas of the body, or combined as a skin care régime. All nine products in the Eucerin Dry Skin range are free from perfume and colourants and are clinically proven to increase moisture levels in the skin. They have been developed to meet the diverse needs of dry skin.

Many people find that they need different emollients for different parts of the body (eg, a heavier emollient for the limbs and a lighter product for the face). They may also find that they need a higher strength product as a treatment. The majority of Eucerin products contain urea in concentrations of 5%, Eucerin Intensive Lotion 10% Cutaneous Emulsion and Intensive 10% Urea Treatment Cream, containing the higher level of urea, are available on prescription for more severe dry skin.

Why urea?
Urea is a natural moisturiser found in healthy skin. People with dry skin lack the normal levels of urea needed to maintain healthy, hydrated skin.
    It binds water molecules in the skin, helping to maintain its natural moisture balance and suppleness.
    Directly rehydrates the skin to soften and reduce cracking and roughness.
    Helps to break the cycle of itching and irritation caused by dry skin, as well as reducing the skin’s moisture loss.    
 
Clinical trials
Eucerin Dry Skin Intensive 10% w/w Urea Treatment Cream1 is effective in the treatments of patients with atopic dermatitis.

Eucerin 10% Urea Cream study findings:
   - Improved xerosis, pruritus and erythema in patients with atopic dermatitis.
    - Reduced trans-epidermal water loss (TEWL) in atopic patients more effectively than urea-free creams.
    - Was easy and pleasant to apply with good absorption.
    - Improved barrier function of the skin.
    Was well tolerated by most patients.

Eucerin Intensive Lotion 10% w/w Cutaneous Emulsion (Urea)2
Efficient hydration of the skin - effective symptom relief in atopic skin. Eucerin 10% Urea Lotion - Improves dry skin symptoms efficiently, reduces symptoms of atopic skin efficiently.

Design
Four-week randomised, double-blind, vehicle controlled
and semilateral study with 60 elderly volunteers (mean
age 64.1 years) with characteristic symptoms of dry aged skin.2

Results
Corneometry results showed that Eucerin 10% Urea Lotion produced greater epidermal hydration compared to that of the urea-free vehicle over four weeks. Skin hydration was still present 12 hours after the application. At all times Eucerin 10% Urea Lotion was found to be significantly superior to its vehicle. Skin dryness and itching improved and decreased during treatment. Eucerin 10% Urea Lotion was proven to be well tolerated.

Conclusion
Eucerin 10% Urea Lotion was proven to be effective and very well tolerated in patients with xerotic dry skin.

References
1.    Pigatto et al., 10% UREA Cream (Laceran) for Atopic Dermatitis a Clinical and Laboratory Evaluation. Journal of Dermatological Treatment 1996,7:171-175 TEWL (grams of water loss in 1hr per m2) in atopic patients and normal subjects during treatment with base cream and Laceran.
2.    Schölermann et al., Efficacy and Safety of Eucerin 10% Urea Lotion in the Treatment of Symptoms of Aged Skin.

Licensing: Product information relating to Eucerin Intensive 10% w/w Urea Treatment Cream and Eucerin Intensive Lotion 10% w/w Cutaneous Emulsion. Marketing authorisation holder: Beiersdorf UK Ltd, Birmingham B37 7YS, UK . Active ingredients Urea EP 10% w/w. Directions: Apply twice daily to the affected areas of the skin. Indications: For the treatment of Ichthyosis, Xeroderma, Hyperkeratosis and Atopic Eczema/Dermatitis and other dry skin conditions. Precautions Do not use if sensitive to any of the ingredients in cream or lotion. Do not use on broken,inflamed skin. Do not apply to large areas of skin on patients with renal insufficiency. This cream or lotion could increase the penetration of some substances, such as medicines known as corticosteroids, dithranol or fluorouracil. Avoid contact with the eyes or other sensitive areas. Keep out of reach of children. For external use only. Legal category GSL PL 14160/0003;PA 1159/1/1 (Cream) GSLPL14160/0004; PA1159/1/2 (Lotion). NHS Price - Pack size and cost 250ml lotion (£7.93), 100ml cream (£7.59). To report any adverse reaction, please contact BDF Consumer Relations on 0845 6448556. Eucerin is a registered trademark. Revised May 2012.

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